Research Technician

Massachusetts General Hospital
United States, Massachusetts, Boston
149 13th Street (Show on map)
Jan 24, 2025
The A.A. Martinos Center for Biomedical Imaging at the Massachusetts General Hospital (MGH), affiliated with Harvard Medical School, is one of the premier brain imaging research centers in the world. The Research Technician (RT) works in a histology/histopathology laboratory directed by Dr. Jean Augustinack. The focus of our laboratory is mapping the healthy human brain and investigating Alzheimer's disease especially its preclinical phase. This position will concentrate on validating neuroimaging but also investigate the cellular pathology in the human medial temporal lobe in Alzheimer's disease with tissue-based methods. The RT is responsible for preparing and processing human tissue specimens, performing histology and pathology protocols, manual MRI labeling, and running quantitative/semi-quantitative data analyses. The RT is responsible for detailed recordkeeping, making figures, and writing publications. Education Bachelor's Degree Field of Study: Biology, Neuroscience, Zoology, or related field. Experience Prior laboratory experience, and knowledge in R/statistics PRINCIPAL DUTIES AND RESPONSIBILITIES: Duties include histopathology experiments on human brain tissue samples, itemized as: sectioning tissue on microtome and mounting tissue on slides performing histochemistry, histopathology and immunohistochemistry staining protocols performing DNA extraction and PCR for AD genotyping documenting data/tissue, microscopic evaluation for histology and histopathology quantifying cell populations and pathology analyze tissue and data quantitatively contribute to and develop new protocols use UNIX workstation in MRI preparing laboratory solutions, ordering supplies, lab equipment maintain a clean & safe lab environment maintain documentation/record keeping, including a lab notebook, protocols, photography SKILLS & COMPETENCIES REQUIRED: committed and hard working eager to learn new skills good attention to detail organized with good record keeping skills works productively and independently but also works well with others maintain productivity in projects independently improves the quality and efficiency of own work demonstrates good judgment, troubleshooting skills Physical Requirements Standing Frequently (34-66%) Sitting Occasionally (3-33%) The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.