MacMillan Center for the Study of the Non-Coding Cancer Genome (CSNCG) Intern
 New York Genome Center | |
remote work
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 United States, New York, New York | |
 Jan 27, 2025 | |
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MacMillan Center for the Study of the Non-Coding Cancer Genome (CSNCG) Intern New York, NY Internship Program Description NYGC's Summer Internship Program is designed to provide students hands-on mentorship from an assigned mentor in one of our research labs, support groups or administrative departments. You will gain exposure to Genomics and the research that we do, as well as have the opportunity to interact and collaborate with top genomic researchers. In addition, NYGC interns will be able to attend and participate in a wide variety of other events scheduled specially for our Summer Intern group, including weekly workshops, presentations, career panels, social events and much more. The expected duration of the internship is June 2nd, 2025- July 25th, 2025. The MacMillan Center for the Study of the Non-Coding Cancer Genome (CSNCG) is a partnership between the MacMillan Family Foundation and the New York Genome Center. The mission of the CSNCG is to dramatically advance our understanding of human physiology and disease mechanisms in cancer through an unprecedented research program focused on understanding the role and function of the non-coding genome and epigenome in cancer evolution, progression, and treatment response. This requires shared innovative technologies and mathematical approaches, and an interdisciplinary effort between theory, measurement, and application. Thus, a key goal of the CSNCG will be the creation of a common causality discovery platform that brings together engineers, data scientists, mathematicians, technologists, and biological experts to engage in collaborative efforts to develop and scale access to tissue-based measurements and computational tools, which will provide quantification of phenotypes as a function of natural or experimental variation of the non-coding genome and epigenome. CSNCG interns will be able to gain experience, training, and exposure to the state-of-the-art technologies and analytical methods being developed and applied within the CSNCG. With access to the NYGC-based faculty, the Technology Innovation and Technology Development labs, the Production Sequencing Lab, as well as the Computational Biology and Software Engineering teams, CSNCG interns will have the unique opportunity to experience a highly integrated, multidisciplinary environment, allowing them to tailor their projects and training to their specific interests, while learning how to navigate the interface of academia and industry in genomic science and gain exposure to the administration and operation of a large, interdisciplinary research program. Each CSNCG intern will be able to participate in one of several different projects, including:
Investigating gene regulatory landscape via 3D genome organization
Investigation of the dark genome influence on targeted and chemotherapy sensitivity in pancreatic cancer organoids and patients
Projects: Single-cell interrogation of noncoding drivers of colon cancer Genome-scale screens for synthetic enhancers of CAR-NK function Massively-parallel CAR engineering for next-generation cell therapies RNA-targeting CRISPR screens to pinpoint oncogenic noncoding RNAs
Joint analysis of double-stranded DNA breaks and transcriptome in single cells
Transcriptomic engineering for tumor cells
Using optical mapping and long-read sequencing to understand complex genomic rearrangements in osteosarcomas
Projects: Enhancing Somatic Variant Detection in African Breast Cancer Genomes Using Graph Pan-Genomes Investigating lncRNA Expression Heterogeneity in Breast Cancer Across Different Ancestral Backgrounds Eligibility requirements
Who Should Apply?
Stipend Interns will earn an $8,000 stipend for their participation in the program. Application Required Documents
Flexible Work NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent in this position is eligible for a flexible work schedule or hybrid remote work arrangement with supervisory approval. At minimum, interns will be required to be onsite at the New York Genome Center for all weekly intern events (e.g. scientific and social events), which will occur once or twice per week. Key Competencies at NYGC
About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity Diversity, equity, and inclusion are central to NYGC's core mission. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery - fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. Position Requirements
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