Research Lab Tech I, Genetics

Brigham and Women's Hospital
United States, Massachusetts, Boston
77 Avenue Louis Pasteur (Show on map)
Feb 12, 2025
Working under the general supervision of Principal Investigator (or Research Manager), and in accordance with established hospital policies and procedures, conducts a variety of routine experiments where methodologies are clearly established. Calculates, transcribes, and analyzes data using basic statistics. May perform literature searches under direction of supervisor. The Cichowski laboratory, a lab within BWH, Harvard Medical School, and the Dana-Farber Harvard Cancer Center, is searching for motivated individuals to fill a Research Assistant position. Our laboratory utilizes biochemical, cellular and mouse modeling approaches to elucidate mechanisms that drive cancer. We then use this insight to develop and test promising therapies with the goal of ultimately translating our findings to the clinic. This is a superb opportunity for someone who is interested in working in a cutting-edge, academic basic research setting on projects with high clinical relevance. This laboratory has a long tradition of integrating research assistants into all scientific aspects of the lab and mentoring them to achieve their career goals. As a Research Assistant you will be part of a preclinical discovery team and your responsibilities will include executing cell culture experiments, mouse colony management, administering therapeutic agents in vivo, and utilizing basic biochemical, molecular biology and imaging techniques to assess efficacy and elucidate mechanisms of action (western blotting, quantitative PCR, cloning, CRISPR editing, possibly ChiP-seq, RNA-seq). 1. Under general supervision, performs a variety of routine tests following established methodologies. Routine tests may include evaluation of protein expression levels by Western Blot, or gene expression by qRT-PCR. 2. Prepares and maintains tissue cultures. 3. Record data, summarizes, and analyzes results using basic statistics. 4. Prepares laboratory reagents, chemicals, instruments, and equipment. 5. Maintains supplies inventory in accordance with departmental procedures. 6. Discusses progress of work regularly with supervisor. 7. All other duties, as assigned. Qualifications * B.S. in a biological or chemical science required. * New graduate with relevant course or project work. * Some experience with mice and tissue culture and/or molecular techniques is preferred. * Good organizational skills, detail oriented. * Sound degree of computer literacy. * Ability to methodically record data and to analyze data using basic statistics. * Ability to perform a variety of routine tests and prioritize work. * Good interpersonal and communication skills. * Ability to demonstrate professionalism. Additional skills: * Excellent organization skills, detail oriented * Interested in working with mice * Ability to methodically record data and analyze using basic statistics * Ability to multi-task and establish daily priorities * Passion for science The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.