Research Services Senior Prof

Job Summary:

This is an Open Rank Laboratory Science position that will support the lab of Dr. Ally Nguyen in the Department of Cell and Developmental Biology at the University of Colorado School of Medicine. The lab professional will contribute to maintaining the lab and conducting basic science research on genome integrity. In the past, we found that the requirements for proteins involved in core-cellular processes can differ significantly across cellular contexts, including across different cell types, within disease, or across species. Our lab is interested in identifying these selectively required genes, specifically those that are involved in cell division and the maintenance of genomic integrity and harnessing these differences as the key to unraveling their function. We are also driven to uncover these selectively required genes as they serve as attractive candidates for targeted therapeutics - genes that could serve as an "Achilles heel" for cancer cells, while minimizing off-target effects to healthy tissues. To approach this, we use targeted and large scale CRISPR/Cas9 based gene editing approaches in mammalian cell lines, in combination will cell biological and molecular techniques.

The successful candidate will work on at least one independent project and will have training, interest, and/or a background in genome regulation. We value a team-based approach to science. As part of this, the successful candidate may at times be tasked to assist other trainees in the lab with their research projects. A significant part of the position will also be to manage the general administration of the lab including ordering, inventory, onboarding of new lab members, and maintenance of lab equipment.

Key Responsibilities:

• Purchasing orders
• Starting/maintaining the lab.
• Experiments using mammalian cell lines, including embryonic cell types
• Perform CRISPR/CAS9 gene knockout screens
• High-resolution microscopy experiments.
• Plasmid design and molecular cloning.
• Transduction experiments using viral vectors

You do not need to be an expert in all the techniques listed, although it would be helpful if you are familiar with some of them. Dr. Nguyen can teach you techniques as long as you are motivated to learn and ask questions.

Work Location:

Onsite - this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

Dr. Nguyen recently opened her lab in the Department of Cell and Developmental Biology, where her research seeks to understand how cells organize and segregate their genomes and how these processes change across diverse cellular contexts. In addition to cutting edge research, Dr. Nguyen highly values mentoring and teaching and has thought deeply about how to create an environment where scientists can grow and gain independence. We are dedicated to developing a research program that not only strives to answer fundamental questions at the forefront of genome biology, but that is inclusive and provides an opportunity for trainees from all backgrounds to succeed and reach their individual and unique goals. As part of this we strongly believe that great science does not occur in isolation and are looking for dedicated and collaborative individuals to join our team.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnically minoritized individuals, persons with disabilities, persons within the LGBTQ+ community and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Entry Level:

• Bachelor's degree in biology, molecular biology, cell biology, genetics, or related field.

Intermediate Level:

• Bachelor's degree in biology, molecular biology, cell biology, genetics, or related field.
• One (1) year professional-level research experience.

Senior Level:

• Bachelor's degree in biology, molecular biology, cell biology, genetics, or related field.
• Two (2) years of professional-level research experience.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master's degree in biology, molecular biology, chemistry, genetics or related field
• Prior experience or background within an experimental or wet lab
• Two (2) years of experience in an experimental or wet laboratory
• Three (3) years of experience in an experimental or wet laboratory
• One to three (1-3) years of experience in an experimental or wet laboratory.
• Two to three (2-3) semesters of experience in an experimental or wet laboratory.

Knowledge, Skills and Abilities:

• Knowledge of basic laboratory techniques including safety procedures and techniques (Entry Level)
• Proficient knowledge of basic laboratory techniques including safety procedures and techniques (Intermediate Level)
• Advanced knowledge of laboratory techniques including safety procedures and techniques (Senior Level)
• Excellent record-keeping and organizational skills
• Ability to work independently and manage time
• Ability to communicate and work with others
• Ability to communicate effectively, both in writing and orally
• Demonstrated commitment to advancing diversity and inclusion
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Outstanding customer service skills
• Demonstrated commitment and leadership ability to advance diversity and inclusion
• Knowledge of basic human anatomy, physiology medical terminology
• Ability to follow complex research protocol information
• Ability to interpret and master complex research protocol information
• Molecular biology skills
• Understanding of basic genetics
• Basic cell biology knowledge

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position. Please also include a description of why you are interested in joining our research group.

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers.

Questions should be directed to: Kate Beatty, Kate.Beatty@cuanschutz.edu

Screening of Applications Begins:

Applications will be accepted until finalists are identified, but preference will be given to complete applications received by February 20, 2025. Those who do not apply by this date may or may not be considered.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as:

Entry Level: $45,000 - $57,240

Intermediate Level: $48,970 - $62,290

Senior Level: $52,941 - $67,341

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.