Medical Director, Imaging Biomarkers, Translational Medicine (San Diego based)

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

Neurocrine Biosciencesis a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visitneurocrine.com, and follow the company onLinkedIn,XandFacebook. (*in collaboration with AbbVie)

About the Role:

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• Lead the design, execution, and interpretation of imaging biomarker studies with a focus on pharmacodynamic endpoints in both healthy volunteers and patient populations

• Apply PET and MRI imaging techniques, including both morphological and functional endpoints, to support early-stage drug development and biomarker validation

• Oversee neuroimaging studies in a clinical research setting, collaborating with internal teams, external partners, and imaging vendors

• Establish and manage relationships with commercial and academic imaging partners, ensuring the highest quality data acquisition and analysis

• Work cross-functionally with translational medicine, clinical development, regulatory affairs, and research teams to integrate imaging biomarker strategies into drug development programs

• Serve as the biomarker lead in development programs, contributing to study protocols, regulatory interactions, and clinical development plans

• Ensure compliance with regulatory and quality standards for imaging biomarker data used in clinical studies

• Contribute to scientific publications, conference presentations, and thought leadership in the field of imaging biomarkers

• Collaborate with biomarker and clinical scientists, as well as clinical development team across the Translational Medicine and Experimental Medicine groups at Neurocrine

Minimum Experience

• MD or equivalent advanced medical degree with a strong scientific background in Clinical Neurosciences, or biomarker-relevant disciplines (Neurology, Neurosurgery, Neuropediatrics, Neuroradiology)

• Minimum 5-10 years of experience in neuroimaging research and biomarker development within a pharmaceutical, biotechnology, government, or academic environment

• Prior experience designing and executing imaging biomarker studies in early clinical development

• Exceptional PhD candidates with extensive (10+ years) clinical imaging research experience will be considered

Preferred Experience

• Board Certification in relevant clinical discipline

• Demonstrated leadership in managing scientific teams and projects

• Excellent communication and presentation skills, with the ability to articulate complex scientific concepts to diverse audiences

• Strong publication record in peer-reviewed journals

• Experience with regulatory filings and interactions with health authorities

• Prior experience working within a GxP-regulated environment

• Extensive experience with PET and MRI imaging methodologies, particularly in the context of pharmacodynamic biomarkers and disease characterization

• Proven ability to independently design and execute neuroimaging studies in clinical trial settings

• Strong expertise in managing imaging vendors, data acquisition, and quality control processes

• Experience in regulatory filings related to imaging biomarkers and interactions with health authorities

• Ability to communicate complex imaging biomarker strategies and findings effectively to senior management, clinical investigators, and external stakeholders

• Strong ability to work in large, matrixed teams with colleagues from multiple disciplines, including clinical operations, regulatory, imaging science, pharmacology, and biostatistics

• Expertise in neuroimaging data interpretation and integration within a translational and clinical development framework

• Ability to make data-driven strategic and tactical decisions in imaging biomarker development

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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