Postdoctoral Fellow, Neuroimmune dysregulation in obesity

Postdoctoral Fellow, Neuroimmune dysregulation in obesity

Stranahan Lab, Department of Neuroscience and Regenerative Medicine Medical College of Georgia,

Augusta University, Augusta, GA USA

Job Summary: We are recruiting a Postdoctoral Fellow for funded investigation into neuroimmune regulation of brain function in obesity. Qualified applicants should have a strong background in cellular or systems neuroscience and extensive experience working with mouse models. Prior training in neuroimmunology is desirable, but motivated and driven candidates with experience in the neuroscience of obesity and metabolic control are also encouraged to apply. Successful applicants will receive intensive support for their professional development and long-term goals.

Research description/Responsibilities: The Stranahan lab aims to understand the pathophysiology of obesity using an integrative approach that captures the complexity of signal generation in peripheral tissues and signal transduction in the brain. We previously characterized neuroimmune feedback mechanisms linking visceral adiposity with hippocampal dysfunction in male mice and subsequently identified neuroprotective immunoregulatory signaling between beige adipocytes in subcutaneous fat and the central nervous system. Our strategy involves working backwards from chronic obesity (and associated metabolic pathophysiology) to earlier-onset dysfunction among specific cell types in vulnerable brain regions. We successfully used this strategy to identify critical windows for neuroinflammation in males and females with dietary obesity, and to characterize the onset and progression of obesity-induced cerebrovascular dysfunction. These studies use a range of techniques including analytical and imaging flow cytometry; tissue clearing and light-sheet microscopy; confocal/multiphoton imaging; stereotaxic and soft tissue surgery; behavioral testing; metabolic phenotyping; brain slice electrophysiology; and routine molecular assays (qPCR, western blotting, ELISA). Applicants do not need prior experience with all listed techniques; motivated candidates will receive didactic and practical training from senior members of the investigative team.

Required Qualifications: Ph.D. degree from an accredited college or university.

Preferred Qualifications: Doctoral degree from an accredited college or university and experience in neuroscience, biology, cell biology or other life sciences directly related to the research area to which the position is assigned; extensive direct experience working with rodent models.

How to Apply: Consider applying with us today!

https://www.augusta.edu/hr/jobs/ Search for Job ID: 272918.

Select University Faculty & Staff > External Applicants if you are a candidate from outside the university.

Select University Faculty & Staff > Internal Applicants if you are a current university employee.

Potential applicants are encouraged to contact Dr. Alexis Stranahan directly with questions about the position or application process (astranahan@augusta.edu). Candidates should submit a cover letter describing previous research experience, educational background, and the desired starting date, along with a CV and contact information for (3) references.

Shift/Salary/Benefits: Shift: Days; Monday - Friday (Work outside of normal business hours is required).

Salary to be commensurate with qualifications of the selected candidate within the established range of the position.

Recruitment Period: Until Filled.

Augusta University offers a variety of benefits to full-time benefits-eligible employees. Benefits that may be elected could include health insurance, dental insurance, life insurance, Teachers Retirement System (or Optional Retirement Plan), as well as earned vacation time, sick leave, and 13 paid holidays. Also, our full-time employees who have been employed with us successfully for more than 6 months can be considered for the Tuition Assistance Program.

About Us:Augusta University is Georgia's innovation center for education and health care, training the next generation of innovators, leaders, and healthcare providers in classrooms and clinics on four campuses in Augusta and locations across the state. More than 10,500 students choose Augusta for educational opportunities at the center of Georgia's cybersecurity hub and experiential learning that blends arts and application, humanities, and the health sciences. Augusta is home to Georgia's only public academic health center, where groundbreaking research is creating a healthier, more prosperous Georgia, and world-class clinicians are bringing the medicine of tomorrow to patient care today. Our mission and values https://www.augusta.edu/about/mission.php make Augusta University an institution like no other.