Associate/Full Project Scientist - Metabolic flux analysis, Stable Isotope Tracer Techniques and Mass Spectrometric Isotope Ratio Analysis-Nutritional Sciences & Toxicology Department

The Nutritional Sciences & Toxicology Department at the University of California, Berkeley seeks applications for an Associate/Full Project Scientist in the Hellerstein Lab, in the area of metabolic flux analysis, stable isotope tracer techniques, and mass spectrometric isotope ratio analysis.

The Hellerstein lab develops novel stable isotope-mass spectrometric techniques for measuring important biochemical, physiologic, and cellular processes in living organisms, including humans. These measurements are used as clinical biomarkers of health and disease and in the basic investigation of metabolic control and integration in complex systems. Our work centers on in vivo metabolic flux analysis, which differs from most contemporary biomedical research in several ways: technically by adding the dimension of time, operationally by requiring dynamic systems analytic methods, and conceptually by integrating disparate control factors in the final readout.

Our laboratory is not defined by traditional disciplines but, by generating new methods, covers fields including metabolic disease, immunology, molecular/ molecular biology, exercise, aging, flux proteomics and metabolic fluxomics, neurobiology, and cancer.

The successful candidate will have access to multiple departments, including molecular and cell biology, integrative biology, statistics, and the Center for Computational Biology, in addition to many research collaborations around the country and internationally.

The position will be responsible for analyzing different metabolic systems and devising optimal flux analysis experimental approaches for a wide variety of questions and biomedical projects.

Specific Duties include:

* Designing and executing experiments involving stable isotope tracers and in vivo flux analysis.

* Data management, and data analysis, including simulation modeling

* Manuscript preparation.

* Present research at international conferences (as oral presentations/posters), peer-reviewed journals (as manuscripts), and on Zoom calls (as PowerPoints)

* Contributing to grant proposals.

* Mentoring students.

* Keep detailed records of experiments performed, conclusions made, and communication of results orally and through lab notebook records.

PhD (or equivalent international degree)

At least 6 years of post-PhD research experience.

1. Experience with designing and executing experiments involving stable isotope tracers and in vivo flux analysis. Flux analyses include data modeling (simulations, computer models), mass spectrometric research and innovations, and deep familiarity with principles of tracer analysis, including combinatorial analysis of mass isotopomers.
2. Experience in metabolic flux analysis, including in vivo tracer study design and complex modeling of metabolic systems (SAAM, other models).
3. Skills and experience with manuscript preparation, presenting research, contributing to grant proposals, and mentoring students.
4. Excellent writing and communication skills and a strong publication record in peer-reviewed journals.

• 1-3 required (contact information only)

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As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment or discrimination, as defined by the employer.
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