New

Research Technician II - Center for Genomic Medicine - Morini/Alves Labs

Massachusetts General Hospital
United States, Massachusetts, Boston
185 Cambridge Street (Show on map)
Jun 27, 2025
The Morini and Alves Laboratories at the Center for Genomic Medicine, Massachusetts General Hospital (MGH), are seeking a highly motivated Research Technician to support ongoing translational research focused on developing gene editing and pharmacological therapies for Familial Dysautonomia (FD), a rare neurodegenerative disorder. The successful candidate will play a key role in testing novel gene editing approaches and small-molecule compounds in a mouse model of FD. This includes conducting efficacy studies, genotyping, tissue processing, behavioral assays, and molecular biology techniques such as qPCR, Western blotting, and RNA analysis. We are looking for a results-driven, team-oriented individual who thrives in a fast-paced and collaborative environment. The ideal candidate is detail-oriented, self-motivated, and comfortable working independently at the bench. A background or strong interest in neuroscience, human genetics, and/or therapeutic development is highly desirable. Prior experience with mouse handling and colony management is strongly preferred. DoesthispositionrequirePatientCare?No EssentialFunctions Executesprotocolsofnon-routineexperiments. AssistsPI with determining the most suitablemethodology. Performsbasicdesignandmodicationofprotocols. Execute and support in vivo efficacy studies using a mouse model of FD. Assist in mouse colony management (breeding, genotyping, health monitoring). Calculates,transcribes,andanalyzesdata. Preparesandpresentsreports. OrganizesandsummarizesacquireddatausingscienticandStatisticalTechniques. Participatesinthedesignofexperimentsoreldwork. JobDescription Education Bachelor'sDegreeRelatedFieldofStudyrequired Canthisroleacceptexperienceinlieuofadegree?Yes LicensesandCredentials Experience PreviousResearchLabExperience1-2yearsrequired Knowledge,SkillsandAbilities Analyticalskillsandabilitytoresolvetechnicalproblems. Abilitytointerpretacceptabilityofdataresults. StrongComputerskills. Demonstratedcompetenceinresearchtechniquesandmethodologies. The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.