TEMP- Associate Scientist / Scientist, Bioanalytical LC-MS

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

Neurocrine Biosciencesis a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visitneurocrine.com, and follow the company onLinkedIn,XandFacebook. (*in collaboration with AbbVie)

The successful candidate will be responsible for developing, optimizing, and implementing LC-MS bioanalytical methods to support the quantitative analysis of small molecules, peptides, and proteins in biological matrices. This position also involves working collaboratively with cross-functional teams to support drug discovery and development programs.

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• Develop and execute LC-MS/MS bioanalytical methods for the quantification of small molecules, peptides, and proteins in biological samples from preclinical Pharmacokinetic and Toxicokinetic studies

• Proficiency in sample preparation techniques for biological matrices, such as solid-phase extraction, protein precipitation and affinity purification

• Strong expertise in LC-MS/MS method development, optimization and troubleshooting on Triple Quadrupole (Sciex or similar) or Orbitrap HRMS

• Perform Pharmacokinetic analysis and modeling using Phoenix Winnonlin

• Collaborate with cross-functional teams to support preclinical studies by providing bioanalytical support and data interpretation.

• Contribute to the preparation of bioanalytical protocols and study reports

• BS/BA degree in analytical chemistry, biochemistry, pharmaceutical sciences, or related discipline and 2+ years of pharmaceutical industry experience OR

• MS/MA degree in chemistry or closely related field preferred and some similar industry experience noted above OR

• PhD in chemistry or closely related field and some industry or relevant experience a plus

• Hands-on experience in bioanalytical method development for various therapeutic modalities using LC-MS/MS

• Excellent communication and interpersonal skills, with the ability to work effectively in a collaborative team environment

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Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.