New

RESEARCH SCIENTIST- PHD-Small Molecule Medicinal Chemistry (temporary)

The Scripps Research Institute
United States, California, San Diego
Jan 13, 2026
Description ABOUT US: Calibr is a first-of-its-kind, nonprofit translational research institute dedicated to creating the next generation of medicines. A division of Scripps Research and situated in the heart of San Diego's Torrey Pines Mesa biomedical research hub, Calibr is uniquely positioned to create and proliferate innovative partnerships. Calibr's research interests span a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected diseases, as well as age-related and degenerative diseases. Calibr was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities. Leveraging the unique scientific framework of Scripps Research, Calibr has created a portfolio of drug candidates based on Scripps technologies and is shaping a new paradigm for advancing nonprofit biomedical research to impact patients while re-investing in further innovative research. Calibr offers scientists from a wide range of disciplines the opportunity to apply their skillsets to creating transformative medicines - if you have a passion in making a difference, this is the opportunity for you. POSITION TITLE: Research Scientist-PHD RESPONSIBILITIE & DUTIES: The Research Scientist job responsibilities include: Good hands-on experience with crystallization, filtration and chromatography-based processing methods along with small molecule analytical methods. Work closely with Calibr's scientists on development of lab-scale synthetic, analytical and formulation projects. Works cross-functionally to deliver high quality compounds in support of Calibr's preclinical drug discovery programs. Prepare technical reports, patent application content, publications and oral presentations as necessary. POSITION REQUIREMENTS: PhD in chemistry, Medicinal Chemistry, synthetic chemistry, bio-organic chemistry or related field with experience in pharmaceutical/drug discovery industry. Proven track record of successfully overseeing structure-activity development. In-depth knowledge of synthetic organic chemistry and pharmacokinetics. Familiarity with common isolation methods including crystallization (batch and continuous mode), filtration and drying. Hands on experience including but not limited to the following analytical methods: RP-HPLC, UV-Vis; HR-MS, LCMS-QTOF, XRD and other analytical methods is required. Excellent interpersonal, verbal and written communication skills. Comfortable in a fast-paced environment and able to adjust based upon changing priorities. Highly motivated, creative, and devoted to project goals. COMPENSATION: The expected hiring range for this position is $78,000-$103,000 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements. ADDITIONAL INFORMATION: This is a temporary position anticipated to end by April 30, 2026. PHYSICAL DEMANDS & WORK ENVIRONMENT: The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions. The above statements describe the level of work performed and expected in general terms. The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice. Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff. EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture, and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status. Equal Opportunity Employer This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.