Senior Systems Architect, Infrastructure & Operations

Lantheus (NASDAQ: LNTH) is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Sweden, Switzerland and United Kingdom, Lantheus has been providing radiopharmaceutical solutions for nearly 70 years.

Today, we're expanding our portfolio and pipeline across oncology, neurology and cardiology. Through recent acquisitions, along with strategic partnerships across the life sciences ecosystem, we are accelerating our efforts to advance precision medicine and improve patient outcomes around the world.

At Lantheus we are purpose-driven, and every employee plays a vital role in our success. We're dedicated to cultivating a high-growth, forward-thinking culture where innovation thrives and diverse perspectives drive meaningful progress.

Join us and be part of a company where your contributions make a real impact, because we know someone's health is in our hands.

Summary of role
We are seeking a visionary Senior Systems Architect to serve as the strategic backbone of Lantheus' modern infrastructure evolution. This isn't just a technical role. It's a partnership position where you'll shape the future of how we operate across on-premises, colocation, cloud, and disaster recovery environments. You'll be a key player who bridges the gap between deep technical mastery and business-driven innovation, transforming infrastructure from a cost center into a competitive advantage. In this pivotal role, you'll architect seamless experiences across Microsoft 365, hybrid virtualization platforms, and AI-driven automation while serving as a trusted advisor to leadership on technology investments that drive measurable cost savings. If you're a systems polymath who owns outcomes end-to-end, thrives at the intersection of security and productivity, and sees infrastructure as the foundation for business transformation, this is your opportunity to leave a lasting imprint on Lantheus' technological future.

This position is based in Massachusetts and requires a presence on-site (two/three) days per week, and open to applicants authorized to work for any employer within the United States.

Key Responsibilities/Essential Functions

* Design and optimize infrastructure spanning on-premises datacenters (VMware ESXi, Nutanix AHV), colocation facilities, and multi-cloud environments (Azure, AWS), ensuring seamless workload mobility and resilience across all tiers.

* Serve as the authoritative voice on M365 architecture, driving adoption of advanced capabilities including Microsoft Purview for data governance, eDiscovery for compliance, and Teams for enterprise collaboration.

* Govern and optimize collaboration platforms across Microsoft Teams, ensuring seamless integrations, security compliance, and adoption strategies that keep the workforce connected.

* Architect and govern identity infrastructure leveraging Okta for workforce identity, designing sophisticated Okta Workflows for automation, and implementing SAML/OIDC integrations that enable zero-friction, zero-trust access across the enterprise.

* Pioneer AI orchestration initiatives that eliminate toil, accelerate provisioning, and introduce intelligent automation across infrastructure operations, positioning Lantheus at the forefront of AIOps adoption.

* Own the end-to-end endpoint strategy encompassing Microsoft Intune for modern management, SCCM for legacy workloads, and Tanium for real-time visibility, third-party patching, and endpoint hygiene at scale. Ensure devices are secure, compliant, and optimized regardless of location.

* Collaborate hand-in-hand with the security team to prioritize, remediate, and validate vulnerability findings, embedding security-by-design principles into every infrastructure decision.

* Design and validate DR architectures that guarantee business continuity, leveraging enterprise backup solutions (e.g., Rubrik) for data protection, conducting regular failover exercises, and maintaining RTO/RPO commitments that protect Lantheus' operations.

* Deliver strategic insights into infrastructure spending, identifying consolidation opportunities, right-sizing recommendations, and licensing optimizations that translate technical decisions into tangible financial impact.

* Serve as the primary technical liaison for managed service providers and technology vendors, establishing SLAs, tracking performance against commitments, and ensuring operational excellence through regular service reviews and escalation management.

* Engage with stakeholders across the organization to understand business objectives, translating them into infrastructure roadmaps that accelerate Lantheus' strategic initiatives.

Requirements

* Bachelor's degree in Computer Science, Information Systems, or equivalent experience. Certifications such as MCSE, Microsoft 365 Certified: Enterprise Administrator Expert, VMware VCP, Nutanix NCP, or Okta Certified Professional are highly valued.

* 10+ years of progressive experience in systems architecture, with demonstrated mastery across hybrid infrastructure environments spanning on-premises, colocation, and cloud platforms.

* Deep expertise in virtualization technologies, including VMware vSphere/ESXi administration and Nutanix AHV/AOS, with proven experience in workload migration, capacity planning, and performance optimization.

* Comprehensive Microsoft 365 proficiency, including Exchange Online, SharePoint, Teams, Microsoft Purview (data classification, DLP, retention), and eDiscovery for legal and compliance requirements.

* Unified communications expertise across enterprise collaboration platforms including Microsoft Teams, with experience managing integrations, governance, and user adoption at scale.

* Identity and access management authority, with hands-on experience implementing Okta (including Okta Workflows for lifecycle automation), SAML 2.0, OIDC/OAuth protocols, and IAM governance frameworks.

* Endpoint management expertise spanning Microsoft Intune for modern device management, SCCM/MECM for traditional workloads, and Tanium for real-time endpoint visibility, third-party patching, and compliance enforcement.

* AI and automation fluency, with experience leveraging AI orchestration tools, scripting languages (PowerShell, Python), and infrastructure-as-code principles to drive operational efficiency.

* Security-minded architecture approach, with demonstrated experience partnering with security teams on vulnerability management, remediation prioritization, and compliance initiatives.

* Financial acumen for technology investments, with a track record of identifying cost optimization opportunities and communicating ROI to executive stakeholders.

* MSP and vendor management experience, with a proven ability to establish SLAs, conduct service reviews, hold providers accountable to contractual commitments, and drive continuous improvement in outsourced operations.

* Exceptional communication and partnership skills, with the ability to translate complex technical concepts into business value and influence decisions at all organizational levels.

* Creative, ownership-driven mindset that thrives in ambiguity, balances competing priorities, and relentlessly pursues solutions that harmonize security, productivity, and cost efficiency.

Core Values

The ideal candidate will embody Lantheus core values:

* Let people be their best

* Respect one another and act as one

* Learn, adapt, and win

* Know someone's health is in our hands

* Own the solution and make it happen

The pay range for this position is between $139,000-$232,000 annually.

Actual base pay offered may vary depending on a number of factors such as job-related knowledge, skills and experience. Employees in this position are eligible for a discretionary performance-based cash incentive, and depending on the level of the role may be eligible for a discretionary annual equity award. Benefits for this position include a comprehensive health benefits package that includes medical, prescription drug, dental, and vision coverage. Other offerings include life and disability benefits, pre-tax accounts, a 401(k) with company contribution, and a variety of other benefits. In addition, employees are eligible for a generous time off package including paid vacation, holidays, sick days, and paid parental leave. Interested candidates can apply at Lantheus.com. Applications for this position will be accepted until March 18, 2026.

Lantheus is an equal opportunity employer that provides a workplace free from discrimination. All qualified applicants and employees are considered without regard to race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any other characteristic protected by law. Lantheus is an E-Verify Employer.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Lantheus Talent Acquisition team at talentacquisition@lantheus.com.