Head of Medical Affairs

JOB TITLE: Head of Medical Affairs

LOCATION: Boston MA DATE PREPARED: February 23, 2026

JOB SUMMARY:

Reporting to the CEO/CMO the Head of Medical Affairs will serve as the functional manager and leader of the Field-based Medical Science Liaison team and provide strategic input into key medical affairs activities, including consistent and aligned medical and scientific communications, cross-functional medical strategy, development and execution of Advisory Boards, KOL and other key customer identification and engagement, publication strategy and planning, CME topics of interest and grant administration, and fostering relationships with key societies, physician networks, oncology cooperative groups and academic institutions. The successful candidate will be someone who has demonstrated success in combining MSL leadership expertise, people-management skills, and medical affairs strategic visionary and tactical operational competencies that resonate with the cross-functional organization.

PRINCIPAL DUTIES:

I. Contribution to Medical Affairs Strategy and Tactics

* Serve as a senior scientific advisor to executive leadership, providing insight into evolving clinical landscapes, competitive dynamics and evidence generation opportunities.

* Develop and own the Medical Affairs strategy aligned to corporate objectives and lifecycle plans, ensuring scientific differentiation and long-term asset value.

* Collaborate with leadership to define strategic initiatives; communicate clearly and frequently to the MSL team and ensure alignment with medical affairs and corporate initiatives

* Define and execute KOL engagement strategy establishing AVEO as a credible and trusted scientific partner. Map scientific influencers and advisory networks.

* Drive external credibility for the organization

* Participate in the development and execution of Medical Affairs activities, such Advisory Boards, Speaker Training, and development of scientific and medical presentation slides

* Provide medical support and a collaborative interface to cross-functional partners (Marketing, Training, Market Access, Clinical Development)

* Establish strong professional rapport with key internal and external customer segments

* Support publication planning (in collaboration with scientific communications, clinical development, and marketing) and contribute to development of evidence-based internal and external scientific/medical content.

* Support medical review of promotional and advertising strategies and implementation

* Contribute to the review, selection, and administration of external educational grants and continuing medical education support activities

* Develop, manage and maintain accountability for the Medical Affairs budget, ensuring strategic allocation of resources across MSL activities, evidence generation, advisory boards, publications, and grants to maximize scientific impact and long-term asset value.

i. Functional Leadership of MSL Team

* Retain (and/or recruit/hire, as needed) a qualified, highly motivated, diverse-thinking, and flexible MSL team

* Oversee and ensure the highest medical and scientific standard and expertise across the MSL team; develop a standard of professionalism that demonstrates the highest regard for established regulatory and legal compliance in accordance with company policies and sound ethical practices

* Actively manage the MSL team by encouraging professional and personal development; lead by example and nurture individual growth, thereby optimizing team performance

* Support and train the team in engaging in compliant scientific exchange about current and emerging therapies, discussions around investigator-initiated trials, and in delivering effective presentations; provide appropriate mentoring and coaching to direct reports with respect to technical skills, business acumen/planning, and effective regional and time management, including frequent field visits with the MSL team

* Work creatively with Medical Affairs leadership to develop meaningful, measurable key performance measures (Key Performance Indicators [KPIs]) to assess and track the success of the MSL team and function and report metrics to Medical Affairs leadership on a regular basis; ensure that goals/performance/ development plans are reviewed on at least a quarterly basis; conducts annual and mid-year performance reviews; create and encourage an environment that stresses open, candid, and timely feedback relative to performance

* Work with MSL team to provide ongoing field updates and insights, including competitive intelligence and Congress coverage, and synthesize this information into meaningful, actionable imperatives

REQUIRED QUALIFICATIONS/EXPERIENCE (BASIC QUALIFICATIONS):

* Advanced Scientific or Medical degree (s), MD preferred

* Demonstrated substantial Medical expertise in Oncology through clinical, research, and business activities

* Minimum of 7 years of experience in medical affairs, with 5 years as an MSL in industry; at least 2 years of experience managing an MSL team

* Demonstrated success in building effective teams, systems, and processes; proven ability to identify, select and manage a variety of external resources related to execution of medical affairs functions

* Ability to lead a team of functional experts and negotiate the multi-disciplinary environment in which they operate

* Strategic and analytical thinking with the ability to contribute to the plan and design effective medical affairs brand and life cycle strategies

* Strong understanding of industry and regulatory guidelines pertinent to compliant interactions with external audiences

* Demonstrated ability to comprehend complex scientific, medical, and relevant business issues and respond with actionable strategies and tactics to effectively produce timely and measurable results

* Excellent written and verbal communication skills, exceptional listening skills, strong presentation skills, and good negotiating and influencing skills

About AVEO

AVEO is a commercial-stage, oncology-focused biopharmaceutical company committed to delivering medicines that provide a better life for patients with cancer. AVEO currently markets FOTIVDA (tivozanib) in the U.S. for the treatment of adult patients with relapsed or refractory renal cell carcinoma (RCC) following two or more prior systemic therapies. AVEO continues to develop FOTIVDA in immuno-oncology combinations in RCC and other indications, and has several other investigational programs in clinical development. AVEO is committed to creating an environment of diversity, equity and inclusion to diversify representation within the Company.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.