Remote

Senior Clinical Project Manager - Inflammation/ Phase 2b (Sponsor-Dedicated /Remote -U.S.)

Syneos Health/ inVentiv Health Commercial LLC
paid time off, sick time, 401(k)
United States, Wisconsin
May 13, 2026
Senior Clinical Project Manager - Inflammation/ Phase 2b (Sponsor-Dedicated /Remote -U.S.) Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress. Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver - for one another, our customers, and, most importantly, for those in need. Discover what your 25,000 future colleagues already know: Why Syneos Health * We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. * We are committed to building an inclusive culture - where you can authentically be yourself. Central to this is our purpose - Driven to Deliver - which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone's life. * We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress. Job Responsibilities Senior Clinical Project Manager - Inflammation / Phase 2b Sponsor Dedicated \| Remote (U.S.-Based) Preference for Hybrid Foster City, CA-Based Candidates Are you an experienced global Clinical Project Manager who has successfully led large, complex international clinical trials from start-up through closeout - and thrives in fast-paced environments where operational leadership, accountability, and collaboration are critical to success? This is an exciting opportunity to join a sponsor-dedicated team supporting highly complex global Phase 2b studies within the inflammation therapeutic area as a U.S.-based Global Study Lead. The studies span multiple regions including North America, Europe, APAC, Japan, and China, offering the opportunity to lead large-scale global clinical programs in a collaborative and highly engaged environment. We are seeking a senior-level clinical operations leader who is confident managing complexity at a global scale while remaining deeply engaged in the operational details required to successfully execute studies across multiple regions, vendors, and stakeholders. The ideal candidate brings strong global study leadership experience, exceptional organizational and communication skills, and the ability to proactively identify risks, drive decisions, and maintain momentum in fast-moving clinical development environments. This is a highly visible role requiring someone who can operate strategically while also remaining hands-on and execution-focused. This team is looking for experienced global project leaders who enjoy taking ownership, leading cross-functional teams, and driving complex studies forward while working alongside leadership that values partnership, communication, and professional development. While remote/home-based candidates may be considered, priority will be given to candidates located in or near Foster City, California, with the ability to work onsite 2-3 days per week. THE ROLE As a Senior Clinical Project Manager - Inflammation / Phase 2b, you will serve as the Global Study Lead responsible for the operational delivery of complex global Phase 2b clinical trials across multiple international regions. You will lead cross-functional study teams, oversee global vendors and CRO partners, manage timelines and operational risks, and ensure seamless study execution from start-up through closeout. This role requires a strong operational leader who can balance strategic oversight with deep involvement in day-to-day study execution. You will partner closely with Clinical Operations leadership, regional teams, vendors, and key stakeholders to drive study performance, maintain inspection readiness, and ensure global alignment across all phases of the clinical trial lifecycle. Success in this role requires strong global clinical trial management expertise, the ability to navigate ambiguity and competing priorities, and a proactive leadership style focused on collaboration, accountability, and execution. WHAT YOU WILL DO Lead and independently manage complex global Phase 2b clinical trials from study start-up through closeout with minimal oversight Serve as the Global Study Lead responsible for operational strategy, execution, timelines, quality, risks, and overall study performance Lead global cross-functional teams across North America, Europe, APAC, Japan, and China to ensure aligned and efficient study execution Maintain detailed oversight of study conduct, proactively identifying operational risks, enrollment challenges, quality concerns, and timeline gaps Drive operational execution while maintaining strong strategic oversight across all phases of the study lifecycle Oversee global vendors and CRO partners to ensure accountability, quality deliverables, inspection readiness, and adherence to study expectations Facilitate study team meetings, governance discussions, and operational reviews while ensuring clear ownership and follow-through on action items Partner closely with stakeholders across Clinical Operations, data management, regulatory, supply chain, and other functional areas Ensure compliance with GCP, SOPs, regulatory requirements, and sponsor expectations across global regions Drive issue escalation, mitigation planning, and resolution in a proactive and solutions-oriented manner Navigate highly matrixed and fast-paced environments while effectively balancing competing priorities and evolving business needs Contribute to process improvements, operational efficiencies, and best practices that support successful global study execution WHO YOU ARE Required Qualifications Significant Clinical Operations and global clinical trial management experience within CRO, biotech, or pharmaceutical environments Proven success independently leading complex global clinical trials from start-up through closeout Strong experience managing large-scale international studies across multiple global regions Demonstrated expertise leading global cross-functional teams and managing complex stakeholder environments Strong vendor oversight and CRO management experience with the ability to drive accountability and execution Ability to operate effectively at both strategic and tactical levels, including deep involvement in operational study details Excellent organizational, communication, risk management, and problem-solving skills Proven ability to manage competing priorities and maintain executional excellence in fast-paced clinical development environments Strong leadership presence with high emotional intelligence and the ability to build credibility across teams and leadership levels Experience navigating complex global operational challenges, timelines, and regional considerations Preferred Qualifications Phase 2b global study leadership experience strongly preferred Inflammation therapeutic area experience preferred Experience managing studies across APAC, Japan, and China regions Experience within sponsor-dedicated or embedded sponsor models Stable career progression demonstrating increasing ownership, operational leadership, and global study complexity Ability to thrive in highly collaborative, high-visibility, and high-accountability environments WHAT MAKES THIS OPPORTUNITY DIFFERENT Opportunity to lead highly visible, large-scale global Phase 2b clinical programs with significant strategic and operational impact Join a collaborative sponsor-dedicated environment with engaged leadership that values partnership, communication, and professional growth Gain exposure to complex international clinical trial execution across North America, Europe, APAC, Japan, and China Work alongside experienced global clinical operations professionals in a highly supportive and team-oriented culture Be empowered to influence operational strategy, drive decisions, and make meaningful contributions to study success Thrive in a fast-paced environment that values ownership, accountability, collaboration, and executional excellence Excellent opportunity for senior Clinical Project Managers seeking broader global responsibility, increased visibility, and continued advancement within clinical operations leadership If you are looking for an opportunity to lead globally visible inflammation programs within a collaborative sponsor environment, this is the kind of role that elevates careers! At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. http://www.syneoshealth.com Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.