Post-Doc Research Associate

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.

Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.

UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.

Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.

The purpose of the post-doctoral position is to conduct research in the Armistead Laboratory, which investigates T-cell responses to cancer. The post-doc will engage in an already started project investigating T-cell responses to cancer and viral antigens presented by HLA-E. The Armistead Lab and collaborators have identified a T-cell receptor that targets virus-derived peptide epitopes presented by HLA-E. HLA-E is overexpressed in many cancers, particularly virally driven cancers, and the research to be conducted by this post-doc will be to further characterize the magnitude and specicity of this T-cell response in both cancer cell lines and normal cells. In addition the post-doc will work to identify additional cancer-associated or virus-derived peptides that are presented by HLA-E.

PhD in related field.

The candidate should should have:
1. PhD in a relevant scientific field (Microbiology, Immunology, Biomedical Engineering, Cell Biology)
2. Experience in mammalian tissue culture methods
3. Experience the retroviral gene transduction in human cell lines and human primary cells
4. Molecular biology experience and significant experience in plasmid and vector design
5. Experience in flow cytometry and cell sorting
6. Experience in T-cell functional assessment and understanding of HLA-restriction
7. Experience in HLA/peptide elution and peptide identification by mass spectrometry

PhD in related field.

For information on UNC Postdoctoral Benefits and Services click here

If you experience any problems accessing the system or have questions about the application process, please contact the University's Office of Postdoctoral Affairs at (919) 962-9982 or send an email to opahr@unc.edu.

Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.

The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.